Effect of global posture reeducation and of static stretching on pain, range of motion, and quality of life in women with chronic neck pain: a randomized clinical trial. Certain physical therapy techniques used during a headache (especially at the beginning) can help to reduce the pain of the attack at least temporarily. Zaproudina et al  found no differences between groups (bonesetting versus exercise plus massage) at one month or one year for pain or disability. Before being referred to our physical therapy service, she had been followed by a headache specialist and treated with several standard medication protocols, as well as with nerve blocks (greater and lesser occipital nerves), the patient related transient improvement. The pain and nausea are so intense that people who have this type often need to go to the hospital.
She participated in 20 sessions twice a week, lasting from 40 to 50 minutes, of global stretching, stretching and cervical traction, as well as myofascial release and deactivation of muscular trigger points. This study had a high risk of bias . Cleland et al compared manual therapy with exercise to electrotherapy with exercise for patients with plantar heel pain . They found manual therapy plus exercise was superior. Because brain hypersensitivity is a dynamic condition influenced by nociceptive inputs17, nociceptive lateralization may facilitate unilateral hypoalgesia in patients with headache18. This may have explained the increased severity of pain on the head, as well as the lower PPT values pre-treatment. Various manual therapy techniques including spinal mobilization [115, 116, 119], spinal manipulation [118, 123], knee mobilization [115–117, 120–124], and knee manipulation  were examined within the review.
Imaging is only indicated in patients with a presence of a «red flag» [46, 69]. None located None located Maigne et al  found manipulation was more effective than placebo for pain relief and disability in the treatment of coccydynia at one month. Licciardone et al  assessed osteopathic manipulative treatment following knee arthroplasty. Zaproudina et al  assessed the effectiveness of traditional bone setting (mobilization) of joints of extremities and the spine for chronic neck pain compared with conventional physiotherapy or massage. The effect of the manipulations was more favorable than the personal exercise program in treating the more intense phase of pain. Imaging is only indicated in patients with a positive neurological exam or presence of a «red flag» [45, 46]. No systematic reviews addressing the role of manual therapy in thoracic spine pain that included randomized clinical trials were located.